Tuesday, July 30, 2013

临床试验费用计算

保健品中国市场利弊
http://www.p5w.net/news/gncj/201305/t20130507_147343.htm


保健品临床规定

-

 http://wenku.baidu.com/view/bb8fb37101f69e314332948d.html


国家食品药品监督管理局
http://app1.sfda.gov.cn/datasearch/face3/dir.html

药物临床费用估算
http://wenku.baidu.com/view/063ad2661ed9ad51f01df208

http://wenku.baidu.com/view/414562e819e8b8f67c1cb9c2.html 


2012

http://wenku.baidu.com/view/aac50524bcd126fff7050b55.html


http://wenku.baidu.com/view/02888b3df111f18583d05a3e.html

http://wenku.baidu.com/view/d297947f27284b73f24250c4.html

保健食品各功能需要做的动物及人体试验

http://wenku.baidu.com/view/02a5536ab84ae45c3b358cbd.html

Sunday, July 14, 2013

Natural Lung Cleanse methods

How to cleanse the lungs using natural remedies

To help avoid respiratory problems, cleansing the lungs using natural remedies is simple. Following a three- to five-day cleansing program is often effective in keeping the lungs working properly.

Diet
Step 1

Remove all dairy products from your diet. Dairy products can impede the digestion process making detoxification slow and difficult.
Step 2

Drink one cup of herbal laxative tea before you go to bed the evening before you begin your lung cleanse. This will help remove toxins in your intestines and rid your system of. There are many brands of herbal laxative teas. "Get Regular" by Yogi is among the top choices.
Step 3

Squeeze two lemons into and eight- to 10- ounce glass of water and drink it before your first meal. Lemons help digest alkalizing foods, which help repair damaged lung tissue.
Step 4

Drink a 10-ounce glass of grapefruit juice with breakfast. Grapefruit juice contains natural antioxidants that promote a healthy respiratory system.
Step 5

Drink a 10-ounce glass of carrot juice between breakfast and your second meal. Carrot juice helps alkalize your blood and is high in  beta-carotene. Beta-carotene produces Vitamin A.


Step 6

Discover the power of Noni juice. Noni juice is extracted from the Noni tree, which grows in Southeast Asia. It is is extremely high in potassium and aids in repairing damaged tissue. Mix 2 oz. of Noni juice with an eight-ounce glass of spring water. Noni juice can be purchased from most health-food stores. There are several brands out there, however, it is important to use pure Noni.
Step 7

Drink one cup of mucus-cleansing tea before dinner. Mucus-cleansing tea is rich in rose hips, ginger and peppermint, which are all strong fighters against congestion and mucus buildup. Cleansing tea is readily available in supermarkets and health-food stores.
Step 8

Drink a 12-ounce glass of of pure cranberry juice before bed. Cranberry juice is a powerful antioxidant and will aid in fighting bacteria in the lungs.  Cranberries also aid in cleansing the blood.


Physical Care
Step 1

Enjoy a 20-minute sauna at least once a day during your lung cleanse. A sauna will help open your pores, allowing toxins to leave the body through perspiration.  If you don't have access to a sauna, sit in a hot bath.
Step 2



Take a brisk walk at least once day.  Maintain a rhythm, inhaling deeply an exhaling slowly without becoming dizzy.
Step 3

Do a mucus cleanse at least once a day or as-needed.  Place five to 10 drops of eucalyptus oil into two quarts of simmering water. Drape a dry hand towel over the back of your head and slowly inhale the steam until the water cools. The oil's properties in the steam will help loosen mucus. Using a Netty pot will cleanse the sinuses and rid your lungs of unwanted mucus.

  清肺化痰成了抽烟的人最为关键的健康问题。以下小编为你推荐一些具有清肺化痰功效的食物,让你通过内调,提高身体免疫力,让肺更健康!
  

咳嗽时,应忌食肥甘、厚味、油腻食物,因这些食物会内伤脾胃,产生内热而加重病情。
  辣椒、芥末、胡椒及烈性酒等辛辣之物均可直接刺激呼吸道粘膜,导致支气管平滑肌充血、水肿甚至痉挛,使咳嗽、气喘加重。
  感染和过敏是诱发咳嗽的重要原因。有过敏体质者咳嗽期间,应尽量减少或忌食海鱼及虾蟹等容易助湿、生痰、上火的海腥食物。
  咳嗽时间较长者,机体内蛋白质消耗很大,因此饮食中要安排一些富含蛋白质的食物,如瘦肉、鸡蛋、牛奶及豆制品等,以增强机体免疫功能。
  维生素C能提高人体对外界有害因素的抵抗力,咳嗽患者应多吃富含维生素C 的食物,如新鲜柑桔、大枣、西红柿、菠菜、大白菜等。而对于长期抽烟的男性来说,食用一些富含维生素C的营养保健品,如OHNA天然维C咀嚼片,可以有效的补充维生素C,帮助人体进行免疫调节。
  维生素A 能维持上皮组织的健康,保护呼吸道粘膜。富含维生素A 的食物有胡萝卜、油菜、动物肝脏、蛋黄等。
  常见的能化痰去咳的食物有:
  1、梨:有生津润燥、清热化痰、主治热病伤津、热咳烦躁等症。
  2、蒜:有化痰止咳之功效。
  3、箩卜:能化痰消胀气。
  4、茼蒿:功效暖胃、养肠、利肠胃、化痰浊。
  5、葫芦:性味甘、淡、平;功效利水通淋。润肺止咳。
  6、竹笋:有消渴、益气、消痰、防止咳嗽等功效。
  7、柿子:有清热、止咳、润肠、化痰止泄等功能。
  8、杏仁:有治疗气喘、咳嗽、气逆、痰聚、气短等症。
  9、百合:有温肺止痰、清热安神、养阴清心等功效。
  10、苹果:有补心益气、生津止咳、降压等功效。
  11、甘蔗:有滋阴润燥,调中和胃,润肺止咳之功效。
  12、生姜:有散寒、止呕、祛之功效。
  13、无花果:健脾清肠、消肿解毒、利咽抗癌的作用,主治消化不良、肠炎、痢疾、便秘、痔疮、喉痛、痈疮疥癣。
  14、海蜇:痰饮咳嗽,肝阳上亢:海蜇皮(漂净)30g,鲜荸荠120g,煮服,兼治淋巴结核。
  15、罗汗果:清肺止咳,肺热咳嗽和风热咳嗽者宜服。可用罗汉果1个,柿饼15克,水煎服食。
  16、荸荠能化痰、清热,对热性咳嗽吐脓痰者尤宜。每次可用鲜荸荠250克,洗净削去皮,用沸水烫一下,生吃,早晚各1次,连吃3~5天。
  17、胖大海:有清热、润肺、止咳作用。因于外感者:胖大海五枚,甘草一钱(3克),炖茶饮服,老幼者可加入冰糖少许。”
  18、鸭蛋:性凉味甘,能清肺热。《日华子本草》还认为鸭蛋“清心腹胸膈热”。《医林纂要》中曾介绍:“鸭蛋补心清肺,止热嗽,百沸汤冲食,清肺火。”凡肺热咳嗽者宜食之。
  19、紫菜性味甘咸而寒,能化痰软坚清热。“咳嗽咯吐臭痰(包括肺脓疡、支气管扩张等):紫菜研细末,炼蜜为丸,每服6克,1日2~3次,饭后服。”凡属肺热咳嗽或风热咳嗽吐痰黄稠腥臭者,食之皆宜。
  20、豆腐:有清热润燥作用。《医林纂要》云:“豆腐清热,止咳,消痰。”凡咳嗽属于风热或肺热者尤宜。亦可选用豆腐皮1张,冰糖适量,加水煮熟后食用,对肺热咳嗽也有治疗效果。(
  小编语录:这些食物都是非常常见的清肺食物,除此之外,如果抽烟的人还需要一些其他的方法来清肺戒烟的话,那么就选择公爵替烟王,能够帮助戒烟人群快速戒烟,而且没有不适感!

Useful Herbal Remedies

Though herbal remedies have long been used as an adjunct treatment therapy, not all herbs used for this health purpose may be backed by rigorous clinical research trials. The University of Maryland Medical Center (UMMC) reports that three herbs -- American ginseng, Asian ginseng and grape seed -- are among the most helpful natural remedies in treating your lung cancer. Other herbs known for their cancer-fighting ability include astragalus, ginger, turmeric and thyme.

Tuesday, June 18, 2013

国内已有进口产品及申请进口流程

http://www.freemerce.com/q/%E8%82%BA%E4%BF%9D%E5%81%A5%E5%93%81
进口批文申请
http://wenku.baidu.com/view/9194dbf9941ea76e58fa046b.html?from=rec
http://wenku.baidu.com/view/5c1f83ed81c758f5f61f67d7.html

定 ppt
http://wenku.baidu.com/view/92303da50029bd64783e2cec.html

益生菌类保健食品申报与审评规定(试行)
http://www.cfs.gov.cn/cmsweb/webportal/W308/A64010618.html

Capsule sizes

Capsule Sizing Information

Capsule Sizing Information
Print Chart that shows Actual Capsule Sizes
"00" holds about 735 mg. "0" size holds about 500 mg. #1 holds about 400 mg. #2 about 300 mg. #3 about 200 mg.
One teaspoon will fill about 7 "0" capsules and about 5 "00" capsules. The weight depends on the density of the powder you are using. Some powders are much denser than others. It also depends on the fineness of the powder. The only way to be sure is to check the weight of each individual material. On a scale accurate to within one-tenth of a gram or even to one-tenth of an ounce or even to a gram, you can weigh 24 empty capsules and then compare with the weight when full. If you only want a small amount of active ingredient, then you can mix with a material such as milk powder or rice powder as a filler. That way you can use "0" or "00" size capsules with various weights of active ingredients.

Detailed Capsule Size Data:

Size 00 0 1 2 3 4
1. Weight
Average weight in mg 118 95 75 60 47 38
Tolerance in mg ± 7 ± 6 ± 6 ± 4 ± 3 ± 3
2. Capacity
Volume in ml 0.91 0.68 0.50 0.37 0.30 0.21
Powder Density - Capsule capacity mg
0.6 g/ml 546 408 300 222 180 126
0.8 g/ml 728 544 400 296 240 168
1 g/ml 910 680 500 370 300 210
1.2 g/ml 1092 816 600 444 360 252
3. Length of the capsules
Body inches 0.796 0.726 0.654 0.601 0.535 0.480
Tolerance inches ± 0.018 ± 0.018 ± 0.018 ± 0.018 ± 0.018 ± 0.018
Body mm 20.22 18.44 16.61 15.27 13.59 12.19
Tolerance mm ± 0.46 ± 0.46 ± 0.46 ± 0.46 ± 0.46 ± 0.46
Cap inches 0.462 0.422 0.385 0.352 0.318 0.284
Tolerance inches ± 0.018 ± 0.018 ± 0.018 ± 0.018 ± 0.018 ± 0.018
Cap mm 11.74 10.72 9.78 8.94 8.08 7.21
Tolerance mm ± 0.46 ± 0.46 ± 0.46 ± 0.46 ± 0.46 ± 0.46
Size 00 0 1 2 3 4
4. External diameter
Body inches 0.322 0.289 0.261 0.239 0.219 0.199
Body mm 8.18 7.34 6.63 6.07 5.57 5.05
Cap inches 0.336 0.300 0.272 0.250 0.229 0.209
Cap mm 8.53 7.64 6.91 6.35 5.82 5.32
5. Overall closed length
Inches 0.917 0.854 0.765 0.709 0.626 0.563
Tolerance inches ± 0.012 ± 0.012 ± 0.012 ± 0.012 ± 0.012 ± 0.012
Mm 23.3 21.7 19.4 18.0 15.9 14.3
Tolerance mm ± 0.30 ± 0.30 ± 0.30 ± 0.30 ± 0.30 ± 0.30

Saturday, May 25, 2013

中药

黄芪(Astragalus mongholius Bunge):黄芪,又名黄耆,为植物和中药材的统称。植物黄芪产于内蒙古山西甘肃黑龙江等地,为国家三级保护植物。中药材黄芪为豆科草本植物蒙古黄芪、膜荚黄芪的根,具有补气固表、利水退肿、托毒排脓、生肌等功效。黄芪的药用迄今已有2000多年的历史,其有增强机体免疫功能、保肝、利尿、抗衰老、抗应激、降压和较广泛的抗菌作用。但表实邪盛,气滞湿阻,食积停滞,痈疽初起或溃后热毒尚盛等实证,以及阴虚阳亢者,均须禁服。

 

冬虫夏草(Cordyceps sinensis Sacc):具有扩张支气管、平喘、祛痰、防止肺气肿的作用。

 

百部(Radix stemonae):性味甘、苦,微温。归肺经。主治润肺下气止咳,杀虫。用于新久咳嗽肺痨咳嗽,百日咳;外用于头虱,体虱,蛲虫病,阴部骚痒。蜜百部润肺止咳。用于阴虚劳嗽。

 

川贝(Bulbus fritillariae cirrhosae):(1) 镇咳作用(2)祛痰作用 

 

黄芩(Radix scutellariae):主治温热病、上呼吸道感染、肺热咳嗽、湿热黄胆、肺炎、痢疾、咳血、目赤、胎动不安、高血压、痈肿疖疮等症。黄芩的临床应用抗菌比黄连还好,而且不产生抗药性。我们借助广谱抗菌作用强的特点,用在真菌培养杂菌感染特厉害,用黄芩提取液效果很好,它是农业病害防治最理想的一味药

 Western Herbs

HERBS or Essential oils to consider ~ Eucalyptus, Thyme, Oregano, Peppermint Horseradish, cayenne 

 

15 top Anti-Inflammatory Herbs & Spiceshttp://studiobotanica.com/15-top-anti-inflammatory-herbs-spices/

As indicated by the ‘highlight’ above, Turmeric & Ginger are at the top of the list in terms of ‘strength’. Use them whenever you can –in your meals
or as a tea. (see the post “Ginger and Turmeric – A perfect marriage’)  

 

 

LUNG herbs

Treating lung problems with herbs

 Licorice, marshmallow, pleurisy root, thyme, coltsfoot, catnip, elecampane, gingko biloba, rosemary, comfrey, and mullein are all good choices whether alone or combined. Mullein is a favorite remedy for lung conditions and grows wild in the North Georgia Mountains. In cases of chronic respiratory problems, mullein should be combined with mulberry bark, cowslip root, elecampane, viola, anise, or thyme. Mullein is considered a mild sedative and an excellent expectorant. When using mullein to treat coughs due to colds, combine with horehound and lobelia.

Herb medicine chest

Mullein (Verbascum thapsus);Elecampane (Inula helenium) ;Echinacea (Echinacea augustifolia);Poke (Phytolacca americana)

Elecampane--The roots are dug in the fall after the plants are established (at least three years) and tinctured in 100 proof vodka for six weeks. Do not use elecampane in capsules.  

Top 10 herbs and spices for strengthening your immune system http://www.naturalnews.com/035530_immune_system_herbs_spices.html#ixzz2UYbyAl4r

 

What Herbs Are Good for Lung Health?

Bloodroot;Pleurisy Root; cayenne; echinacea 

 

Top 10 immune system boosters

 

 

dosage of 3 herbs to improve immune

How Astragalus, Cat´s Claw and Echinacea can really boost your immune system.

Astragalus
should be taken with meals at a total intake of 2,000 to 3,000 mgs per day.

echinacea
Recommended dosage appears to vary from 900 mgs to 1200 mgs per day divided into three equal doses. No significant side effects have been reported in the German research, although echinacea should not be used for more than eight weeks at a time as it thins the blood.

cat claw
one gram a day on an empty stomach.


Herbs useful for body cleansing
Birch, celery, common heather.


Complete lung herbs list and annotation

my Formula base

1. Antioxidant
   Acai berry power (dose)
2. Anti-inflammation
   ?EGCG, COCO extract
3. bronchial epithelial cilia beat frequency
 dry extract BNO 1011?, Cayenne, Thyme
4. Lung-Protective
 mullein, thyme,

5. Enhance immune sysytem
gensen
Astragalus
should be taken with meals at a total intake of 2,000 to 3,000 mgs per day.

echinacea
Recommended dosage appears to vary from 900 mgs to 1200 mgs per day divided into three equal doses. No significant side effects have been reported in the German research, although echinacea should not be used for more than eight weeks at a time as it thins the blood.

Tuesday, May 21, 2013

Existing formulas

http://ethnichealthcourt.com/2013/02/08/how-to-detoxify-your-lung/
http://www.care2.com/greenliving/3-herbs-to-boost-your-lungs.html?page=1

Products

1.Dr Schulze's Lung Formula

2. Bronchial and Lung Formula

3. Lung Formula (Brain Child)

4. Lung Formula tablets, certified organic

5. Herbal Lung Formula

6. ALJ (Nature's Sunshine) 

7. AllerTrex™ (Lung Cleanse Formula)

8. Lung Flush

9. Lung Rejuvenator ( Blessed Herbs)

Ingridents

1. 

Herbal Ingredients:Lobelia Leaf & Seed, Elecampane Root, Coltsfoot Leaf, Horehound Leaf, Licorice Root, Kola Nut, Coffee Bean, Cherry Bark, Thyme Leaf, Fennel Seed, Peppermint Leaf, Essential Oil

2.

Ingredients:
Garlic, Myrrh, Thyme, Solomon’s Seal, Monatomic Proprietary Blend, USP Natural Vegetable Glycerin, Mullein, Fennel, Cleavers

3.

4.Supplement Facts:
Serving size: 1 tablet
Servings per container: 90
Each 500 mg tablet contains: Licorice root (Glycyrrhiza glabra)**, Cane Sugar **, Pippali fruit (Piper longum)**, Elecampane root (Inula helenium)**, Vasaka leaf (Adhatoda vasika)**, Amalaki fruit (Emblica officinalis)**, Bibhitaki fruit (Terminalia belerica)**, Haritaki fruit (Terminalia chebula)**, Tulsi leaf (Ocimum sanctum)**, Cardamom seed (Elettaria cardamomum)**, Cinnamon bark (Cinnamomum cassia)**

 

 

 

5. Proprietary Herbal Blend 200 mg †
† Daily Value not established.

Serving Size 1 Capsule
Amount Per Serving % Daily Value

Chickweed powder (Stellaria media) (herb)
Coltsfoot powder (Tussilago farfara) (herb)
Mullein leaf powder (Verbascum thapsus)
Fenugreek seed powder (Trigonella foenum graceum)
Myrrh gum powder (Commiphora myrrha) (oleo-gum-resin)
Nettles leaf powder (Urtica diocia)
Yarrow flowers powder (Achillia millefolium) (flower)
Alfalfa powder (Medicago sativa) (leaf)


6. Lung Formula

Mullein (Verbascum thapsus) - Ideal for the environmental allergy symptoms of bronchitis; asthma, emphysema, chest congestion and many respiratory health problems. Also acts as an expectorant.

White Horehound (Marrubium vulgare) - Helpful in lung congestion, laryngitis and whooping cough.

Coltsfoot (Tussilago farfara) – This herb contains a high percentage of mucilage and saponins with beneficial effects on respiratory system. Proven to support the natural relaxation of the bronchial muscles. In combination with others, it is outstanding for maintaining healthy lung function.

Lungwort (Pulmonaria officinalis) – Controls excess mucous and provides nutrition for the lungs; helps restore respiratory health to the lungs’ and bronchial tubes’ linings; aids in relaxing bronchial muscles, and works toward the right amount of mucous.

Lungmoss (Lobaria pulmonaria) Long used by British Columbians for coughing, and in Europe and India for lung ailments.

Garden Violet (Viola odorata) This herb is for difficult breathing and coughs, bronchitis and phlegm. Contains vitamins A and C.

Soap Bark (Quillaja saponaria) Used for cough, conditions of the respiratory tract, and chronic bronchitis. It’s been shown to relax bronchial muscles. 

 

7. AllerTrex™

AllerTrex™ Supplement Facts

8. Lung Flash

INGREDIENTS PER 1000 ml
Rosemary 208 g/l
Scutellaria baicalensis 128 g/l
Momordica grosvenori 128 g/l
Honeysuckle 120 g/l
Chrysanthemum morifolium 120 g/l
Morus alba 72 g/l

 

9. Lung Rejuvenator

Detailed Look at the Lung Rejuvenator Formula
Mullein leaf
expectorant, tones mucous membranes of respiratory system
Pleurisy root
bronchial dilator, stimulates lymph drainage from the lungs
Lungwort lichen
supports lung tissue, soothing expectorant
Grindelia aerial parts
expectorant, antispasmodic, relaxes smooth muscles
Elecampane root*
Relaxing mucilage, stimulating expectorant
Chlorella
heavy metal detoxifier
Cordyceps mycelia CS-4 extract 2:1
increases activity of body's antioxidants, superoxide dismutase, removes blockages in lungs
Turkey Tails mushroom extract 8:1
heals lung disorders, clears dampness, reduces phlegm
Wild American Ginseng root
adaptogenic, restorative tonic
Mullein flower
anti-irritation
Lobelia aerial parts
relaxes bronchials
Long Pepper fruit
breaks up lung congestion
Black Peppercorns*
stimulates circulation
Ginger root*
stimulates lungs
Sweet Violet leaf & flower
supports lungs
Licorice root*
harmonizes formula
distilled water, grain alcohol*, and vegetable glycerine
*Certified Organically Grown, all others wildcrafted with care.
Caution:
Do not take if pregnant or nursing.

 

7. Lung formula8. Lung formula

Ingredients: Garlic, Rose Hips, Rosemary, Echinacea Root, Thyme. Other Ingredients: Vegetarian source capsule. 

 https://www.blogger.com/blogger.g?blogID=2026784144278116356#editor/target=post;postID=8029969719446964504